| 发明名称 | Alpha-oxoacyl amino-caprolactam derivative | ||
| 摘要 | The purpose of the present invention is to provide a pharmaceutical composition that is useful for the treatment of diseases that are caused by an increase in bone resorption and that does not cause serious side effects even when used in combination with another drug. The present invention relates to: an α-oxoacyl amino-caprolactam derivative that is represented by formula (I); (in the formula, X is —O— or —N(R1)— and R1 represents an alkoxycarbonyl group having 1-10 carbon atoms); and a bone resorption inhibitor containing the α-oxoacyl amino-caprolactam derivative. | ||
| 申请公布号 | US9636346(B2) | 申请公布日期 | 2017.05.02 |
| 申请号 | US201615263969 | 申请日期 | 2016.09.13 |
| 申请人 | Seikagaku Corporation | 发明人 | Kobayashi Nobuo;Koji Tsuneo;Kunii Hisatomo;Ishikawa Mizuho;Morita Daisuke |
| 分类号 | A61K38/00;A61K31/55;C07K5/02;C07K5/065 | 主分类号 | A61K38/00 |
| 代理机构 | Mintz Levin Cohn Ferris Glovsky and Popeo, P.C. | 代理人 | Mintz Levin Cohn Ferris Glovsky and Popeo, P.C. ;Corless Peter F.;Cowles Christopher R. |
| 主权项 | 1. A method for treating osteoporosis in a subject comprising administering to the subject a pharmaceutical composition comprising a compound of formula (I): wherein X is —O— or —N(R1)—, wherein R1 is a (C1 to C10 alkoxy)carbonyl group, and a pharmaceutically acceptable carrier, thereby treating osteoporosis in the subject. | ||
| 地址 | Tokyo JP | ||