Device for dosing and dry nebulization

摘要

The invention relates to a device (1) for dosing and dry nebulization of nebulizable material, comprising a nebulization channel (3), which has a first attachment piece and a second attachment piece, and a source of compressed carrier gas connected to the first attachment piece via a valve for the purpose of sending a carrier gas pressure pulse into the nebulization channel. The device is characterized in that between the first attachment piece and second attachment piece, and above the nebulization channel, a reservoir open only towards the nebulization channel, and used for receiving the nebulizable material, is connected to the nebulization channel such that it is gas-tight with respect to the environment, and that, when the valve is closed, a pressure compensation takes place in the nebulization channel and in the reservoir. The invention also relates to the use of this device for inhaled administration of a powdered pharmaceutical preparation, and to a method for dosing and dry nebulization of nebulizable material by means of such a device.

主权项

1. A device for dosing and dry nebulization of nebulizable material, comprising:
a nebulization channel connected to a source of compressed carrier gas; a valve configured to send a carrier gas pressure pulse into the nebulization channel; a reservoir above and open only towards the nebulization channel, the reservoir configured for receiving the nebulizable material and connected to the nebulization channel such that the reservoir is gas-tight with respect to an external environment; a conical dosing chamber separate from and connecting to the reservoir; and a capillary tube connecting the valve to the nebulization channel, the capillary tube having an outlet in the nebulization channel in an area under the connection between the reservoir and the nebulization channel, wherein an inner diameter of the capillary tube is smaller than an inner diameter of the nebulization channel, such that upon release of the carrier gas pressure pulse the capillary tube and the nebulization channel form a jet pump flowing the carrier gas past the connection between the reservoir and the nebulization channel and generate an underpressure in the reservoir, and wherein when the valve is closed, a pressure compensation takes place by carrier gas flowing back to the reservoir.