| 发明名称 | Process for the preparation of <i>N</i>-iodoamides | ||
| 摘要 | The present invention provides new stable crystalline N-iodoamides-1-iodo-3,5,5-trimethylhydantoin (1-ITMH) and 3-iodo-4,4-dimethyl-2-oxazolidinone (IDMO). The present invention further provides a process for the preparation of organic iodides using N-iodoamides of this invention and recovery of the amide co-products from waste water. | ||
| 申请公布号 | US9637462(B2) | 申请公布日期 | 2017.05.02 |
| 申请号 | US201415034751 | 申请日期 | 2014.11.05 |
| 申请人 | Technion Research & Development Foundation Limited | 发明人 | Nisnevich Gennady;Kulbitski Kseniya;Gandelman Mark;Artaryan Alexander |
| 分类号 | C07D263/26;C07D275/06;C07D233/82;C07C41/22;C07D233/74;C07D263/22;C07D209/48;C07C17/093;C07C29/64;C07C41/05;C07C67/05;C07C201/12;C07D211/38;C07C17/10;C07C17/12;C07C17/14;C07C17/363;C07B39/00;C07D207/46 | 主分类号 | C07D263/26 |
| 代理机构 | McDonnell Boehnen Hulbert & Berghoff LLP | 代理人 | McDonnell Boehnen Hulbert & Berghoff LLP |
| 主权项 | 1. A process for the preparation of organic iodide comprising the steps of: (a) reacting an amide with iodine and [bis(acyloxy)iodo]arene in aprotic solvent to yield N-iodoamide and iodoarene as co-product; (b) reacting an organic compound with said N-iodoamide of step (a) to yield desired organic iodide and amide as co-product; and (c) recovering said amide co-product from the reaction mixture of step (b); wherein said amide is 4,4-dimethyloxazolidin-2-one, saccharin or 3,5,5-trimethylhydantoin and said N-iodoamide is 3-iodo-4,4-dimethyloxazolidin-2-one (IDMO), N-iodosaccharin (NISac) or 1-iodo-3,5,5-trimethylhydantoin (1-ITMH), respectively. | ||
| 地址 | Haifa IL | ||