发明名称 |
Method for shaping tissue matrices |
摘要 |
Methods for shaping tissue matrices are provided. The methods can be used to produce shaped tissue products that retain desired biologic properties without using chemical crosslinking agents. |
申请公布号 |
US9636435(B2) |
申请公布日期 |
2017.05.02 |
申请号 |
US201113177720 |
申请日期 |
2011.07.07 |
申请人 |
LifeCell Corporation |
发明人 |
Sun Wendell;Monteiro Gary |
分类号 |
A61L27/36;A61L27/50 |
主分类号 |
A61L27/36 |
代理机构 |
McCarter & English, LLP |
代理人 |
McCarter & English, LLP ;Van Eman Matthew R. |
主权项 |
1. A method for shaping a tissue matrix, comprising:
selecting a collagen-containing tissue matrix; partially dehydrating the tissue matrix; applying mechanical forces to the tissue matrix to change the orientation of collagen fibers within the tissue matrix; and exposing the tissue matrix while partially dehydrated to ionizing radiation to cross-link at least a portion of the tissue matrix. |
地址 |
Branchburg NJ US |