发明名称 Method for shaping tissue matrices
摘要 Methods for shaping tissue matrices are provided. The methods can be used to produce shaped tissue products that retain desired biologic properties without using chemical crosslinking agents.
申请公布号 US9636435(B2) 申请公布日期 2017.05.02
申请号 US201113177720 申请日期 2011.07.07
申请人 LifeCell Corporation 发明人 Sun Wendell;Monteiro Gary
分类号 A61L27/36;A61L27/50 主分类号 A61L27/36
代理机构 McCarter & English, LLP 代理人 McCarter & English, LLP ;Van Eman Matthew R.
主权项 1. A method for shaping a tissue matrix, comprising: selecting a collagen-containing tissue matrix; partially dehydrating the tissue matrix; applying mechanical forces to the tissue matrix to change the orientation of collagen fibers within the tissue matrix; and exposing the tissue matrix while partially dehydrated to ionizing radiation to cross-link at least a portion of the tissue matrix.
地址 Branchburg NJ US