SITU SELF-ASSEMBLING PRO-NANOPARTICLE COMPOSITIONS AND METHODS OF PREPARATION AND USE THEREOF

摘要

Pharmaceutical composition comprising a pharmaceutically acceptable oil phase, a surfactant, and a therapeutic agent are provided herein, wherein the composition is in the form of a pro-nanoparticle or a self-assembling nanoparticle. Additionally, these pharmaceutical compositions have high loading of the therapeutic agent. Also provided herein are methods of preparing the pharmaceutical compositions and methods using the compositions in the treatment of a patient.

主权项

1. A pharmaceutical composition comprising:
(a) a therapeutic agent; (b) a pharmaceutically acceptable oil phase; (c) a surfactant, wherein the composition is formulated as a pro-nanoparticle composition.