METHODS AND MATERIALS FOR TREATING HYPERTENSION

摘要

This document provides methods and materials involved in treating hypertension (e.g., age-associated hypertension, resistant hypertension, or chronic refractory hypertension). For example, methods and materials involved in administering one or more sympatholytic agents to a patient to identify the patient as having an elevated baseline level of sympathetic nerve activity and performing renal denervation on the identified patient to reduce a symptom of hypertension (e.g., resistant hypertension) are provided.

主权项

1. A method for treating hypertension, wherein said method comprises:
(a) administering one or more sympatholytic agents to a mammal having hypertension, (b) detecting a greater than 20 mmHg reduction in blood pressure during or after said administration of said one or more sympatholytic agents to said mammal, and (c) ablating a renal nerve within said mammal, wherein a symptom of said hypertension is reduced following said step (c).