NANOPORE WITH A CAVITY FOR FILTERING POLYMERS

摘要

Various embodiments are described herein a membrane that may be used to affect the translocation of polymers through at least one nanopore in the membrane by incorporating an enlarged cavity within the nanopore where the cavity size is selected along with an external force strength so that a translocation time of polymers through the nanopore is affected and may result in a non-monotonic function of polymer chain length, provide a low-pass application or a bioreactor application, for example. Various combinations of such membranes may be used in polymer filtration devices.

主权项

1. A membrane for affecting the translocation of polymers therethrough, wherein the membrane comprises:
a first side having a cis opening; a second side having a trans opening, the second side being located opposite the first side; and a nanopore extending between the cis opening of the first side to the trans opening of the second side, the nanopore including a cavity that has a cavity size that is selected to affect translation time of polymers having certain chain lengths when the nanopore is influenced by an external force.