| 发明名称 |
OPHTHALMIC COMPOSITION |
| 摘要 |
The present invention relates to ophthalmic compositions for treatment of conditions in the eye. More specifically, the present invention relates to ophthalmic compositions comprising a polyquaternium compound and an anionic polymer. Methods for reducing and/or preventing the incompatibility of polyquaternium compounds with anionic polymers are also disclosed. |
| 申请公布号 |
US2017112933(A1) |
申请公布日期 |
2017.04.27 |
| 申请号 |
US201514922504 |
申请日期 |
2015.10.26 |
| 申请人 |
Johnson & Johnson Consumer Inc. |
发明人 |
Bai Mingqi;Holeva Kenneth T. |
| 分类号 |
A61K47/12;A61K9/08;A61K31/728;A61K31/715;A61K31/78;A61K9/00;A61K47/34 |
主分类号 |
A61K47/12 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A composition comprising:
a. from about 10 ppm to about 1000 ppm of a polyquaternium compound having a weight average molecular weight of from about 150 to about 15,000 Daltons; b. from about 0.001% to about 0.5% of an anionic polymer having a weight average molecular weight of from about 250 to about 4,000,000 Daltons; and c. an effective amount of an organic acid, salts thereof or mixtures thereof, such that the organic acid binds with the polyquaternium compound at at least a 1:1 molar ratio;wherein the composition is substantially free of cationic oligomer compounds and precipitation inhibiting compounds. |
| 地址 |
Skillman NJ US |
