| 发明名称 |
NEW METHOD FOR PRODUCING OUTER MEMBRANE VESICLES |
| 摘要 |
The present invention relates to ex vivo method for producing outer membrane vesicles (OMVs) by expression or overexpression of the hemolysin F gene (hlyF) in gram-negative bacterium. |
| 申请公布号 |
US2017112913(A1) |
申请公布日期 |
2017.04.27 |
| 申请号 |
US201415302279 |
申请日期 |
2014.04.07 |
| 申请人 |
INSERM (INSTITUT NATIONALL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) ;CENTER NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS ;INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (INTRA) ;UNIVERSITÉ PAUL SABATIER TOULOUSE III ;CENTRE HOSPITALIER UNIVERSITAIRE DE TOULOUSE |
发明人 |
OSWALD Eric;MARTIN Patricia;MURASE Kazunori |
| 分类号 |
A61K39/108;C12N1/02;C12Q1/18;C12N1/06 |
主分类号 |
A61K39/108 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. An ex vivo method for producing outer membrane vesicles (OMVs) comprising
expressing or overexpressing a hemolysin F gene (hlyF) in gram-negative bacterium; and recovering the OMVs from the gram-negative bacterium. |
| 地址 |
Paris FR |
