| 发明名称 |
POLYPEPTIDE-POLYMER CONJUGATES AND METHODS OF USE THEREOF |
| 摘要 |
The present invention provides polypeptide-polymer conjugates. A subject polypeptide-polymer conjugate is useful in a variety of applications, which are also provided. |
| 申请公布号 |
US2017112899(A1) |
申请公布日期 |
2017.04.27 |
| 申请号 |
US201615214398 |
申请日期 |
2016.07.19 |
| 申请人 |
The Regents of the University of California |
发明人 |
Healy Kevin Edward;Wall Samuel T.;Saha Krishanu;Schaffer David V. |
| 分类号 |
A61K38/17 |
主分类号 |
A61K38/17 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A conjugate of the formula:
[X—(Y)n]10-50—Z, where X is a biologically active polypeptide having a molecular weight of from about 5 kDa to about 50 kDa; Y is an optional linker moiety, wherein n is 0 or an integer from 1 to about 10; and Z is a biocompatible polymer having a molecular weight of at least about 50,000 Daltons, and wherein the polypeptide is covalently linked to the polymer directly or via the linker moiety. |
| 地址 |
Oakland CA US |
