CONTROLLED RELEASE DELIVERY DEVICE COMPRISING AN ORGANOSOL COAT

摘要

A controlled release delivery device for controlled release of an active ingredient comprising: (i) a core particle comprising the active ingredient homogenously dispersed or dissolved therein; and (ii) an organosol polymeric coat comprising a homogenous mixture of, (a) a water soluble gel forming polymer and a water insoluble organosoluble polymer in a dry weight ratio of from about 20:80 to about 50:50, (b) an organosolvent, and (c) an anti-tacking agent; the organosol polymeric coat being applied directly to and substantially enveloping the core particle.

主权项

1. A method for providing site specific, timed, pulsed, chronotherapeutic, or extended delivery of an active ingredient, said method comprising:
controlling release of said active ingredient by a controlled release delivery device for controlled release of said active ingredient comprising: (i) a core particle comprising the active ingredient homogenously dispersed or dissolved therein; and (ii) an organosol polymeric coat comprising a homogenous mixture of,
(a) a water soluble gel forming polymer and a water insoluble organosoluble polymer in a dry weight ratio of from about 20:80 to about 50:50,(b) an organosolvent, and(c) an anti-tacking agent; the organosol polymeric coat being applied directly to and substantially enveloping the core particle.