| 发明名称 |
USE OF PROTEIN S100A12 AS A MARKER FOR COLORECTAL CANCER |
| 摘要 |
The present invention relates to the diagnosis of colorectal cancer. It discloses the use of protein S100A12 in the diagnosis of colorectal cancer. It relates to a method for diagnosis of colorectal cancer from a stool sample, derived from an individual by measuring S100A12 in said sample. Measurement of S100A12 can, e.g., be used in the early detection or diagnosis of colorectal cancer. |
| 申请公布号 |
US2017115294(A1) |
申请公布日期 |
2017.04.27 |
| 申请号 |
US201715399801 |
申请日期 |
2017.01.06 |
| 申请人 |
Roche Diagnostics Operations, Inc. |
发明人 |
Wild Norbert;Garczarek Ursula;Geistanger Andrea;Andres Herbert;Hagmann Marie-Luise;Karl Johann;Krause Freidemann;Pfeffer Michael;Rollinger Wolfgang;Tacke Michael;Thierolf Michael |
| 分类号 |
G01N33/574 |
主分类号 |
G01N33/574 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for diagnosing colorectal cancer in an individual comprising the steps of:
(a) providing a stool sample from the individual, (b) contacting the sample with a specific binding agent for S100A12 under conditions whereby a complex will form between said binding agent and any S100A12 that may be present in said sample, (c) determining the amount of the complex formed in step (b), and (d) correlating the amount of complex determined in (c) to the diagnosis of colorectal cancer. |
| 地址 |
Indianapolis IN US |
