发明名称 |
CHEMICAL REGENERATION METHOD OF OXIDIZED COENZYME NAD (P)+ |
摘要 |
It discloses a chemical regeneration method of oxidized coenzyme NAD(P)+ which is under an oxygen or air atmosphere condition, adding a catalytic amount of bridged flavin, and oxidizing NAD(P)H to obtain NAD(P)+. The catalyst for regeneration of cofactor is cheap and easily available small organic molecule having no noble metal; this regeneration system can regenerate NADH and NADPH; this regeneration system has a wide pH range and temperature range, being applicable to various oxidation reactions catalyzed by nicotinamide-dependent oxidoreductase. |
申请公布号 |
US2017114085(A1) |
申请公布日期 |
2017.04.27 |
申请号 |
US201615159029 |
申请日期 |
2016.05.19 |
申请人 |
NANJING TECH UNIVERSITY (CN) |
发明人 |
Ying Hanjie;Zhu Chenjie;Li Qing;Tan Zhuotao;Pu Lingling |
分类号 |
C07H19/207;C12P19/36 |
主分类号 |
C07H19/207 |
代理机构 |
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代理人 |
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主权项 |
1. A method for regenerating chemically an oxidized coenzyme NAD(P)+, characterized in that, under an oxygen or air atmosphere condition, adding a catalytic amount of a bridged flavin, and oxidizing NAD(P)H to obtain NAD(P)+. |
地址 |
Nanjing CN |