| 主权项 |
1. A compound having a structure according to Formula I or II:wherein
R1a, R1b, R7a, and R7b are independently selected from H, substituted or unsubstituted alkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heteroalkyl, and substituted or unsubstituted heterocycloalkyl;
and R1a and R1b, together with the carbon atom to which they are attached, are optionally joined to form a ring which is a member selected from substituted or unsubstituted C3-C7 cycloalkyl and substituted or unsubstituted 3- to 7-membered heterocycloalkyl;and R7a, and R7b, together with the carbon atom to which they are attached, are optionally joined to form a ring which is a member selected from substituted or unsubstituted C3-C7 cycloalkyl and substituted or unsubstituted 3- to 7-membered heterocycloalkyl;wherein at least one of R1a, R1b, R7a, and R7b is not H; and R8 is selected from H, wherein Lx is selected from a bond, substituted or unsubstituted alkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heteroalkyl, and substituted or unsubstituted heterocycloalkyl;Lxs is selected from substituted or unsubstituted alkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heteroalkyl, and substituted or unsubstituted heterocycloalkyl;Rs is selected from a protected or unprotected reactive functional group, a linkage site, and a solid support; andRx is selected from a protected or unprotected reactive functional group and a linkage site;wherein each linkage site is covalently bound to a member independently selected from a nucleoside, a linker to a nucleoside, a nucleotide, a linker to a nucleotide, an oligonucleotide, a linker to an oligonucleotide, a nucleic acid, a linker to a nucleic acid, a carrier molecule, a linker to a carrier molecule, a solid support, and a linker to a solid support. |
