PHARMACEUTICAL COMPOSITIONS COMPRISING GELS AND METHODS FOR FABRICATING THEREOF

摘要

Pharmaceutical compositions are described, the compositions comprising a therapeutically effective quantity of an active component and a quantity of a sterile gel. Methods for fabricating the compositions and using them for ophthalmic applications are also described.

主权项

1. An ophthalmological pharmaceutical composition for treating dry eye syndrome, the composition comprising:
(a) a therapeutically effective quantity of an active component that is free of any of fluconazole, methazolamide, azitromycin, mitomycin, pilocarpine, povidone-iodine, dexamethasone, flurbiprofen, bromfenac, nepafenac, diclofenac, ketorolac, indomethacin, suprofen, norfloxacin, ciprofloxacin, antiseptics comprising the NH4+ cation or pharmaceutically acceptable isomers, salts, hydrates or solvates thereof, the active component comprising at least one medicament for dry eye syndrome treatment, the active component optionally being an immunosuppressant; and (b) a quantity of a thermoreversible gel component that is free of any of chitosan, carbopol or polysorbate.