| 发明名称 |
METHODS OF TREATING CANCER USING PD-1 AXIS BINDING ANTAGONISTS AND MEK INHIBITORS |
| 摘要 |
The present invention describes combination treatment comprising a PD-1 axis binding antagonist and a MEK inhibitor and methods for use thereof, including methods of treating conditions where enhanced immunogenicity is desired such as increasing tumor immunogenicity for the treatment of cancer. |
| 申请公布号 |
US2017112925(A1) |
申请公布日期 |
2017.04.27 |
| 申请号 |
US201715399118 |
申请日期 |
2017.01.05 |
| 申请人 |
Genentech, Inc. |
发明人 |
JUNTTILA Melissa |
| 分类号 |
A61K39/395;A61K31/4523;C07K16/28 |
主分类号 |
A61K39/395 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for treating or delaying progression of cancer in an individual comprising administering to the individual an effective amount of a PD-1 axis binding antagonist and a MEK inhibitor, wherein the individual has cancer or is at risk of developing cancer that is resistant to a B-raf antagonist. |
| 地址 |
South San Francisco CA US |
