Copolymers having polyisobutylene and biodegradable polymer segments

摘要

The present invention pertains to copolymers having one or more polyisobutylene segments and one or more biodegradable polymer segments, to methods of making such copolymers, to medical articles that contain such copolymers, and to methods of making such medical articles. According to certain aspects of the invention, copolymers are provided, which comprise a plurality of polyisobutylene segments and a plurality of biodegradable polymer segments. According to certain aspects of the invention, copolymers are provided, which comprise urethane linkages, urea linkages, amide linkages, ester linkages, anhydride linkages, carbonate linkages, linkages commonly described as “click” chemistry linkages, and combinations of two or more types of such linkages.

主权项

1. A medical article, comprising:
a tubular member including a polymeric region, the polymeric region including a copolymer comprising a plurality of polyisobutylene segments having a number average molecular weight of 20,000 or less and a plurality of hard biodegradable polymer segments; and wherein the copolymer includes one or more linkages comprising a 1,2,3-triazole moiety.