| 发明名称 | Administering antibodies or fragments thereof which bind hemopexin for the treatment of ocular diseases | ||
| 摘要 | Administering antibodies or fragments thereof which bind hemopexin for use in the treatment of retinal diseases, in particular a retinal disease in which there is a dysfunction of the external blood-retinal barrier, the dysfunction being an impairment of the blood-retinal barrier. Pharmaceutical and veterinary compositions are also disclosed in which the antibodies or fragments thereof are present. The compositions may be applied in wide spectra of ocular diseases. | ||
| 申请公布号 | US9631030(B2) | 申请公布日期 | 2017.04.25 |
| 申请号 | US201314398110 | 申请日期 | 2013.04.29 |
| 申请人 | FUNDACIÓ HOSPITAL UNIVERSITARI VALL D'HEBRON—INSTITUT DE RECERCA | 发明人 | Hernández Pascual Cristina;Simó Canonge Rafael |
| 分类号 | C07K16/40;C07K16/18;A61K39/00 | 主分类号 | C07K16/40 |
| 代理机构 | Hamilton, DeSanctis & Cha LLP | 代理人 | Scull Peter B.;Hamilton, DeSanctis & Cha LLP |
| 主权项 | 1. A method for the treatment of a retinal disease in which there is a dysfunction of the external blood retinal barrier, the dysfunction being a non-hemorrhagic impairment of the blood retinal barrier, the method comprising: administering a therapeutically effective amount of an antibody or a fragment thereof that specifically binds to hemopexin, together with pharmaceutical excipients or carriers, in a patient. | ||
| 地址 | Barcelona ES | ||