| 发明名称 |
Quinolinone-carboxamide compounds as 5-HT4 receptor agonists |
| 摘要 |
The invention provides novel quinolinone-carboxamide 5-HT4 receptor agonist compounds. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with 5-HT4 receptor activity, and processes and intermediates useful for preparing such compounds. |
| 申请公布号 |
US9630960(B2) |
申请公布日期 |
2017.04.25 |
| 申请号 |
US201615139592 |
申请日期 |
2016.04.27 |
| 申请人 |
Theravance Biopharma R&D IP, LLC |
发明人 |
Marquess Daniel;Fatheree Paul R.;Turner S. Derek;Long Daniel D.;Choi Seok-Ki;Goldblum Adam A. |
| 分类号 |
C07D451/02;C07D451/04 |
主分类号 |
C07D451/02 |
| 代理机构 |
|
代理人 |
Hagenah Jeffrey A.;Saxon Roberta P. |
| 主权项 |
1. 1-isopropyl-2-oxo-1,2-dihydro-quinoline-3-carboxylic acid {(1S,3R,5R)-8-[3-formylamino-2-hydroxypropyl]-8-azabicyclo[3.2.1]oct-3-yl}amide of formulaor a pharmaceutically-acceptable salt thereof. |
| 地址 |
South San Francisco CA US |
