发明名称 |
Substituted N-acetyl-L-cysteine derivatives and related compounds |
摘要 |
Novel substituted N-acetyl-L-cysteine (NAC) derivatives and related compounds and methods of using these compounds for the treatment of diseases and/or conditions, including but not limited to diseases and/or conditions of, or involving, the Central Nervous System (CNS), including schizophrenia adrenoleukodystrophy, mitochondrial diseases (e.g. Leigh syndrome, Alpers' disease, and MELAS), Huntington's disease, trichotillomania, HIV-associated neurocognitive disorder, hypoxic-ischemic encephalopathy, drug craving, and drug addiction. |
申请公布号 |
US9630937(B2) |
申请公布日期 |
2017.04.25 |
申请号 |
US201414535855 |
申请日期 |
2014.11.07 |
申请人 |
Promentis Pharmaceuticals, Inc. |
发明人 |
Neary Michael;Nieman James;Tanis Steven;Lawton Daniel;Smith Garry |
分类号 |
A61K31/265;C07D277/14;C07D241/08;C07C323/58;C07C323/59;C07C323/57;C07C327/04;C07C327/34;C07C327/32;C07C329/06;C07D327/04;C07C323/60 |
主分类号 |
A61K31/265 |
代理机构 |
Leydig, Voit & Mayer, Ltd. |
代理人 |
Leydig, Voit & Mayer, Ltd. |
主权项 |
1. A compound of formula |
地址 |
Milwaukee WI US |