Compositions and methods for increasing lifespan and health span

摘要

Disclosed herein are compounds, extracts, and active fractions of the plant Geum japonicum and methods for increasing longevity and survival potency or for preventing or treating various medical conditions, including diabetes, inflammation, wound healing, bed sores, and ocular disorders. The compounds provided herein can be formulated into pharmaceutical compositions and medicaments that are useful in the disclosed methods. Also provided are the use of the compounds and extracts in preparing pharmaceutical formulations and medicaments.

主权项

1. A method for increasing longevity in a non-diseased animal subject, the method comprising administering to the subject an effective amount of an organic extract of Geum japonicum (OEGJ), wherein the effective amount of the extract is at least 200 mg/kg/day, and wherein the organic extract is a methanol extract or an ethanol extract.