<i>Clostridium difficile </i>sporicidal compositions

摘要

Disclosed are sporicidal compositions, and methods of use thereof. The sporicidal compositions contain water, an organic solvent, and a spore-germinating agent containing an iodide source, a citrate source or both. The compositions have sporicidal activity against, e.g., Clostridium difficile spores. The sporicidal compositions can be used alone, or can form part of a disinfecting composition or an antiseptic composition.

主权项

1. A sporicidal composition, comprising:
water; an amount qs of organic solvent, wherein qs is about 5% to about 60% w/w; and an amount qg1 of spore-germinating agent, wherein qgi is about 0.05% to about 5% w/w; wherein:
the organic solvent comprises a glycol, glycerine, a glycol ether, a polyethylene glycol or dimethyl isosorbide; andthe spore-germinating agent comprises:
an amount qi1 of iodide source, oran amount qc1 of citrate source, ora combination thereof;wherein:
qg1≧qi1+qc1; andat least one of qi1 and qc1 is at least about 0.05% w/w.