发明名称 Capsule with soluble blocking element
摘要 The invention relates to a capsule comprising an inlet and an outlet connected by a passage, in which a dissolvable blocking element and a composition to be orally administered are arranged. The blocking element is fluid permeable and, in a non-dissolved condition, is arranged in the passage to block delivery of the composition to an outlet of the passage. The invention further relates to a method for releasable sealing a capsule comprising a composition to be orally administered, comprising the steps of providing the composition chamber in a passage and filling composition into the composition chamber. The passage formed by the capsule is occluded with a blocking element and the blocking element comprises dissolvable material and has a fluid permeable structure.
申请公布号 US9629810(B2) 申请公布日期 2017.04.25
申请号 US200913063045 申请日期 2009.09.09
申请人 SANDOZ AG 发明人 Schwarz Franz Xaver
分类号 A61K9/48;A61M15/00;A61J3/07;A47G21/18;A61J7/00 主分类号 A61K9/48
代理机构 Manelli Selter PLLC 代理人 Melcher Jeffrey S.;Manelli Selter PLLC
主权项 1. A capsule suitable for releasably storing a composition to be administered, the capsule defining a passage, in which the composition to be administered is arranged, the capsule comprising: a middle cut section having a substantially constant cross section and a tapered section at each end of the capsule; a controllable blocking element in the form of a one-way valve, wherein the one-way valve is part of the capsule and comprises a plurality of movable lids obstructing an outlet of the passage at an end of the passage, the one-way valve providing a flow direction through the passage towards the outlet and blocking in the opposite flow direction, wherein the movable lids are an integrally formed part of the capsule, the moveable lids being provided by a wall section of the capsule located at one end of the capsule, the wall section having cuts to form the movable lids separated by the cuts; and an inlet at another end of the passage opposed to the outlet as well as a fluid permeable, non-dissolvable retainer, the retainer being arranged between the composition and the inlet of the capsule to block any flow of the composition through the retainer towards the inlet, wherein the ends of the capsule are hemispherical, the cuts being axially symmetric with respect to a longitudinal axis of the capsule, and the cuts start from an apex of the hemispherical end and extending radially outward.
地址 Basel CH