Internal dry powder delivery system and method thereof

摘要

An internal dry powder delivery system through a working channel of an endoscopic cannula for directly applying the powder form medication to an internal tissue/organ site, includes an elongated tubular delivery channel and a powder supply device for producing pressurized gas mixing with the dry powder for feeding to form a mixture of dry powder and pressurized gas delivering to an internal tissue/organ site through the delivery channel via endoscopic cannula. It ensures a smooth powder release by preventing liquid from accumulation at the tip of the delivery channel and offers physicians a new powder form drug delivery method via endoscope. Also, it offers new minimal invasive application by directly and precisely applying the powder format drug to the internal sites of human gastrointestinal organ via endoscope to achieve hemostasis, anti-inflammation, anti-ulcer and anti-tumor treatment, etc.

主权项

1. A method of delivering dry powder to an internal operation site of beings, comprising the steps of:
(a) extending a distal end of an elongated tubular delivery channel to a position that an emitting opening of said delivery channel is adjacent to said internal operation site; (b) generating a working gas flow containing pressurized gas to mix with dry powder to deliver a mixture of dry powder and pressurized gas to said delivery channel until a predetermined amount of said mixture of dry powder and pressurized gas sprays out from said emitting opening of said delivery channel for application onto said internal operation site; (c) generating a maintaining gas flow to said delivery channel for preventing gas reflux of said delivery channel so as to prevent reflux of gas and fluid into said delivery channel, wherein said pressurized gas is mixed with said dry powder in a gas powder chamber to deliver said mixture of dry powder and pressurized gas from said gas powder chamber into said delivery channel, wherein an outlet of said gas powder chamber is communicatively linked to said delivery channel; and (d) bypassing said maintaining gas flow to said gas powder chamber, such that said maintaining gas flow does not pass through said gas powder chamber.