发明名称 | Tetrahydropyranyl amino-pyrrolopyrimidinone and methods of use thereof | ||
摘要 | The application relates to a compound of Formula (I):; or a pharmaceutically acceptable salt thereof, tautomer, prodrug, solvate, metabolite, polymorph, analog or derivative thereof, which modulates the activity of BTK, a pharmaceutical composition comprising the compound of Formula (I), and a method of treating or preventing a disease in which BTK plays a role. | ||
申请公布号 | US9630968(B1) | 申请公布日期 | 2017.04.25 |
申请号 | US201514757745 | 申请日期 | 2015.12.23 |
申请人 | ArQule, Inc. | 发明人 | Lapierre Jean-Marc;Eathiraj Sudharshan;Namdev Nivedita;Schwartz Brian;Ota Yusuke;Momose Takayuki;Tsunemi Tomoyuki;Inagaki Hiroaki;Nakayama Kiyoshi |
分类号 | C07D487/04 | 主分类号 | C07D487/04 |
代理机构 | Cooley LLP | 代理人 | Cooley LLP ;Pavao Matthew;Chen Chen |
主权项 | 1. A compound of Formula (I): or a pharmaceutically acceptable salt thereof, tautomer, prodrug or solvate thereof. | ||
地址 | Burlington MA US |