发明名称 Tetrahydropyranyl amino-pyrrolopyrimidinone and methods of use thereof
摘要 The application relates to a compound of Formula (I):; or a pharmaceutically acceptable salt thereof, tautomer, prodrug, solvate, metabolite, polymorph, analog or derivative thereof, which modulates the activity of BTK, a pharmaceutical composition comprising the compound of Formula (I), and a method of treating or preventing a disease in which BTK plays a role.
申请公布号 US9630968(B1) 申请公布日期 2017.04.25
申请号 US201514757745 申请日期 2015.12.23
申请人 ArQule, Inc. 发明人 Lapierre Jean-Marc;Eathiraj Sudharshan;Namdev Nivedita;Schwartz Brian;Ota Yusuke;Momose Takayuki;Tsunemi Tomoyuki;Inagaki Hiroaki;Nakayama Kiyoshi
分类号 C07D487/04 主分类号 C07D487/04
代理机构 Cooley LLP 代理人 Cooley LLP ;Pavao Matthew;Chen Chen
主权项 1. A compound of Formula (I): or a pharmaceutically acceptable salt thereof, tautomer, prodrug or solvate thereof.
地址 Burlington MA US