| 发明名称 | Benzamides and related inhibitors of factor XA | ||
| 摘要 | Novel benzamide compounds including their pharmaceutically acceptable isomers, salts, hydrates, solvates and prodrug derivatives having activity against mammalian factor Xa are described. Compositions containing such compounds are also described. The compounds and compositions are useful in vitro or in vivo for preventing or treating coagulation disorders. | ||
| 申请公布号 | US9629831(B2) | 申请公布日期 | 2017.04.25 |
| 申请号 | US201514742465 | 申请日期 | 2015.06.17 |
| 申请人 | Millennium Pharmaceuticals, Inc. | 发明人 | Zhu Bing-Yan;Huang Wenrong |
| 分类号 | C07D213/75;A61K31/44;C07C237/42;C07C255/60;C07C257/18;C07C259/18;C07C311/16;C07C311/46;C07C317/40;C07C317/44;C07D213/81;C07D213/82;C07D217/22;C07D231/12;C07D233/56;C07D233/64;C07D249/08;C07D295/125;C07D333/38;C07D401/12;C07D409/12;C07D409/14;A61K31/616;A61K45/06;A61K9/20;A61K9/48 | 主分类号 | C07D213/75 |
| 代理机构 | Sheppard Mullin Richter & Hampton LLP | 代理人 | Sheppard Mullin Richter & Hampton LLP |
| 主权项 | 1. A method for preventing or treating venous thrombosis in a human patient in need thereof comprising administering to said patient a tablet comprising a maleate salt of the following compound: | ||
| 地址 | Cambridge MA US | ||