| 发明名称 |
Modified Antimicrobial Peptides |
| 摘要 |
The present invention relates to modified antimicrobial peptides which incorporate a histidine tag, are conjugated with a fatty acid and/or are PEGylated and their use in the treatment of microbial infections. |
| 申请公布号 |
US2017107254(A1) |
申请公布日期 |
2017.04.20 |
| 申请号 |
US201515301472 |
申请日期 |
2015.04.02 |
| 申请人 |
NovaBiotics Limited |
发明人 |
O'NEIL Deborah;MERCER Derry;DUNCAN Vanessa |
| 分类号 |
C07K7/08 |
主分类号 |
C07K7/08 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A modified peptide comprising from 3 to 50 D and/or L arginine amino acids except for 0, 1 or 2 substitutions and wherein the peptide further comprises a modification which is selected from one or more of the group consisting of:
1) incorporation of a histidine tag; 2) lipidation; and 3) PEGylation. |
| 地址 |
Aberdeen GB |
