| 发明名称 |
CYTOKINE-CHITOSAN BIOCONJUGATES AND METHODS OF USING THE SAME |
| 摘要 |
Compositions including chitosan covalently linked to a cytokine or growth factor are provided herein. The compositions can be used to produce pharmaceutical compositions and can be used in methods of treating a variety of diseases or disorders. The compositions are especially suitable for localized delivery and may allow for intratamoral delivery and treatment of cancers or stimulation of an immune response to a co-administered antigen. |
| 申请公布号 |
US2017106092(A1) |
申请公布日期 |
2017.04.20 |
| 申请号 |
US201515315097 |
申请日期 |
2015.06.01 |
| 申请人 |
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS |
发明人 |
Zaharoff David A.;Thallapuranam Suresh Kumar;Koppolu Bhanu prasanth;Jayanthi Srinivas;Smith Sean G. |
| 分类号 |
A61K45/00;A61K39/39;A61K38/20 |
主分类号 |
A61K45/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A composition comprising chitosan covalently linked to a cytokine or a growth factor, wherein the cytokine or growth factor is biologically active. |
| 地址 |
Little Rock AR US |
