| 发明名称 |
TREATMENT OF IMMUNE DISORDERS |
| 摘要 |
The present disclosure relates to stem cells which express high levels of Angeopoetin-1 (Ang1) and uses thereof in inhibiting M1-type macrophage production and treating inflammatory disease such as diabetes. |
| 申请公布号 |
US2017106023(A1) |
申请公布日期 |
2017.04.20 |
| 申请号 |
US201515317673 |
申请日期 |
2015.06.01 |
| 申请人 |
Mesoblast International Sarl |
发明人 |
Itescu Silviu;Simmons Paul |
| 分类号 |
A61K35/28;A61K38/18;A61K9/00;A61K35/545 |
主分类号 |
A61K35/28 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of increasing production and/or function of anti-inflammatory cells in a subject in need thereof, the method comprising administering to the subject a composition comprising genetically unmodified stem cells wherein said genetically unmodified stem cells express angiopoietin-1 (Ang1) in an amount of at least 0.1 μg/106 cells. |
| 地址 |
Meyrin CH |
