SINGLE-DOSE ADMINISTRATION OF FACTOR VIIa

摘要

The present invention provides methods for preventing and/or treating bleeding episodes by administering a single dose of a Factor VIIa equivalent. Preferably, the single dose comprises between about 150 and about 500 ug/kg Factor VIIa equivalent.

主权项

1. A method for treating a bleeding episode in a subject in need of such treatment, said method comprising administering intravenously to said subject a Factor VIIa equivalent, wherein said administering is in a single dose and said dose comprises a single-dose-effective amount of said Factor VIIa equivalent and wherein, subsequent to said administration, no further Factor VIIa equivalent is administered to said subject for a period of at least 4 hours.