发明名称 |
COMPOSITIONS AND METHODS RELATING TO TREATMENT OF INFECTION |
摘要 |
Microbial keratitis is a sight threatening disorder and infections result in ocular pain, stromal destruction, corneal thinning and/or perforation, leading to vision loss, if untreated and the need for transplantation. Methods of treating bacterial infection of the cornea prophylactically or therapeutically in a subject, are provided according to aspects of the present invention which include administering an effective dose of glycyrrhizin, or a pharmaceutically acceptable salt, hydrate, solvate, ester, amide, isomer or derivative thereof characterized by anti-bacterial activity, to the subject. |
申请公布号 |
US2017106007(A1) |
申请公布日期 |
2017.04.20 |
申请号 |
US201615297438 |
申请日期 |
2016.10.19 |
申请人 |
Wayne State University |
发明人 |
Hazlett Linda D. |
分类号 |
A61K31/704;A61K45/06;A61K9/00 |
主分类号 |
A61K31/704 |
代理机构 |
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代理人 |
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主权项 |
1. A method of treating Pseudomonas aeruginosa infection of the cornea prophylactically or therapeutically in a subject, comprising:
administering an effective dose of glycyrrhizin, or a pharmaceutically acceptable salt, hydrate, solvate, ester, amide, isomer or derivative thereof, to the subject, thereby treating Pseudomonas aeruginosa infection of the cornea prophylactically or therapeutically in the subject. |
地址 |
Detroit MI US |