ANTIBODIES TO DISULFATED HEPARIN DISACCHARIDE IN THE DIAGNOSIS OF NEUROPATHY

摘要

Methods aiding in the diagnosis of certain neuropathies are disclosed, in which the titer of antibodies to a disulfated heparin disaccharide is assessed in a test sample from a subject. Also disclosed are apparatus and kits that can be used in the methods of the invention.

主权项

1. A detection antibody that specifically binds a human antibody that specifically binds to an isolated or synthesized disulfated heparin disaccharide, wherein the detection antibody comprises a detectable label, wherein the human antibody is human IgM antibody, and wherein the titer level of the detection antibody is indicative of the levels of autoantibody against disulfated heparin disaccharide in a test sample from a subject.