| 发明名称 |
MEDICAMENTS, USES AND METHODS |
| 摘要 |
Description of a composition comprising an antibody molecule and an agent for use in the treatment of refractory cancer and/or relapsed cancer, and of a method of treating refractory cancer and/or relapsed cancer comprising administering an antibody molecule and an agent. There are also described kits comprising the antibody molecule and agents. |
| 申请公布号 |
US2017107293(A1) |
申请公布日期 |
2017.04.20 |
| 申请号 |
US201515311016 |
申请日期 |
2015.05.15 |
| 申请人 |
BIOINVENT INTERNATIONAL AB |
发明人 |
Frendéus Björn;Teige Ingrid;Mårtensson Linda;Cragg Mark;Roghanian Ali |
| 分类号 |
C07K16/28;C07K16/30 |
主分类号 |
C07K16/28 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A composition comprising:
(i) an antibody molecule that specifically binds a cell surface antigen of a target cell, which antibody molecule has a Fc domain capable of binding FcγRIIb; in combination with (ii) an agent that prevents or reduces FcγRIIb binding to the Fc domain of the antibody molecule; characterized in that the composition is for use in the treatment of relapsed cancer and/or refractory cancer in a subject, and that the subject has target cells that express FcγRIIb. |
| 地址 |
Lund SE |
