发明名称 THERAPEUTIC USE OF SPECIFIC LIGAND IN MSRV ASSOCIATED DISEASES
摘要 A ligand includes each of the complementary-determining regions (CDRs) set forth in SEQ ID No. 1, SEQ ID No. 2, SEQ ID No. 3 SEQ ID No. 4, SEQ ID No. 5 and SEQ ID No. 6 or any sequence having either number of substituted aminoacids within said sequences as indicated in the following, from 0 to 3 in CDR1 (SEQ ID No.1), from 0 to 2 in CDR2 (SEQ ID No.2), from 0 to 2 in CDR3 (SEQ ID No.3), from 0 to 1 in CDR4 (SEQ ID No.4), from 0 to 4 in CDR5 (SEQ ID No.5), from 0 to 2 in CDR6 (SEQ ID No.6), or aminoacids substituted with other aminoacids having equivalent chemical functions and properties, within said sequences SEQ ID No. 1 to SEQ ID No. 6.
申请公布号 US2017107274(A1) 申请公布日期 2017.04.20
申请号 US201615367864 申请日期 2016.12.02
申请人 GENEURO SA 发明人 BERNARD Corinne;LANG Alois Bernhardt;PERRON Herve;BERTRAND Jean-Baptiste
分类号 C07K16/10 主分类号 C07K16/10
代理机构 代理人
主权项 1. A method of prophylactically or therapeutically treating diabetes, comprising administering an effective amount of a ligand to a patient in need of prophylactic or therapeutic treatment of diabetes, wherein the ligand comprises each of the complementary-determining regions (CDRs) having the amino acid sequences set forth in SEQ ID No. 1, SEQ ID No. 2, SEQ ID No. 3, SEQ ID No. 4, SEQ ID No. 5 and SEQ ID No. 6.
地址 Plan-Les-Ouates CH