发明名称 |
THERAPEUTIC USE OF SPECIFIC LIGAND IN MSRV ASSOCIATED DISEASES |
摘要 |
A ligand includes each of the complementary-determining regions (CDRs) set forth in SEQ ID No. 1, SEQ ID No. 2, SEQ ID No. 3 SEQ ID No. 4, SEQ ID No. 5 and SEQ ID No. 6 or any sequence having either number of substituted aminoacids within said sequences as indicated in the following, from 0 to 3 in CDR1 (SEQ ID No.1), from 0 to 2 in CDR2 (SEQ ID No.2), from 0 to 2 in CDR3 (SEQ ID No.3), from 0 to 1 in CDR4 (SEQ ID No.4), from 0 to 4 in CDR5 (SEQ ID No.5), from 0 to 2 in CDR6 (SEQ ID No.6), or aminoacids substituted with other aminoacids having equivalent chemical functions and properties, within said sequences SEQ ID No. 1 to SEQ ID No. 6. |
申请公布号 |
US2017107274(A1) |
申请公布日期 |
2017.04.20 |
申请号 |
US201615367864 |
申请日期 |
2016.12.02 |
申请人 |
GENEURO SA |
发明人 |
BERNARD Corinne;LANG Alois Bernhardt;PERRON Herve;BERTRAND Jean-Baptiste |
分类号 |
C07K16/10 |
主分类号 |
C07K16/10 |
代理机构 |
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代理人 |
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主权项 |
1. A method of prophylactically or therapeutically treating diabetes, comprising administering an effective amount of a ligand to a patient in need of prophylactic or therapeutic treatment of diabetes,
wherein the ligand comprises each of the complementary-determining regions (CDRs) having the amino acid sequences set forth in SEQ ID No. 1, SEQ ID No. 2, SEQ ID No. 3, SEQ ID No. 4, SEQ ID No. 5 and SEQ ID No. 6. |
地址 |
Plan-Les-Ouates CH |