| 主权项 |
1. A method of fabrication for a biological fluid sensor for analyzing at least one analyte in human biological fluid, said biological fluid sensor comprising electronic, electrochemical and chemical components, the method comprising:
fabricating a substrate; fabricating a circuit on the substrate; picking and placing the electronic components onto the circuit; reflow soldering of the circuit; fabricating at least two electrodes, wherein the at least two electrodes are comprised of at least one active electrode and at least one reference electrode; fabricating a membrane on the at least one active electrode; sealing and curing the at least one active electrode to create a sealed circuit; and fabricating a dressing;wherein the step of fabricating the at least two electrodes further comprises:
fabricating a metallization paste; constructing the least one reference electrode by applying the metallization paste on top of at least one first trace metal of the circuit and annealing; and constructing the least one active electrode by applying the metallization paste on top of at least one second trace metal of the circuit and annealing,wherein the step of fabricating the dressing further comprises:
laser cutting a sheet of a top cover medical textile, wherein the top cover medical textile has an adhesive side; mechanically placing the sealed circuit on top of the adhesive side of the top cover medical textile, wherein the at least two electrodes are facing up; laser cutting a microfluidic management layer; circumferentially surrounding the at least two electrodes with the microfluidic management layer; laser cutting a sheet of double-sided adhesive to create a double-sided adhesive layer; mechanically placing the double-sided adhesive layer on top of the sealed circuit such that the double-sided adhesive layer covers the sealed circuit; and pressing the top cover medical textile, the microfluidic management layer, the sealed circuit, and the double-sided adhesive layer for permanent bond. |
