发明名称 |
Fluorinated benzofuran derivatives |
摘要 |
The invention relates to fluorinated compounds and their use in the field of pathological syndromes of the cardiovascular system. Novel fluorinated benzofuran derivatives of amiodarone and pharmaceutically acceptable salts or solvates thereof and their use for the treatment of arrhythmias are described. |
申请公布号 |
US9624189(B2) |
申请公布日期 |
2017.04.18 |
申请号 |
US201313796248 |
申请日期 |
2013.03.12 |
申请人 |
SciFluor Life Sciences, Inc. |
发明人 |
Duggan Mark E.;Furuya Takeru;Edwards D. Scott |
分类号 |
A61K31/34;C07D307/80 |
主分类号 |
A61K31/34 |
代理机构 |
Cooley LLP |
代理人 |
Cooley LLP ;Elrifi Ivor R.;Erlacher Heidi A. |
主权项 |
1. A compound of formula II:or a pharmaceutically acceptable salt or solvate thereof, wherein X2 is CF3 and X3 is selected from hydrogen, I, F, CF3, CHF2, CH2F, OCF3, OCHF2, and OCH2F. |
地址 |
Cambridge MA US |