Osteoclast inhibitors for bone marrow lesions

摘要

Oral dosage forms of osteoclast inhibitors, such as nitrogen-containing bisphosphonates, can be used to treat or alleviate pain or related conditions.

主权项

1. A method of treating a bone marrow lesion comprising: selecting a patient having 1) a bone marrow lesion and 2) OARSI Grade 0 or Kellgren and Lawrence Grade 0 or Grade 1 of joint space narrowing, and administering an inhibitor of osteoclast activity to the patient for the treatment of the bone marrow lesion, wherein the inhibitor of osteoclast activity is olpadronic acid, incadronic acid, ibandronic acid, risedronic acid, cimadronic acid, etidronic acid, or tiludronic acid.