Estimation of alignment parameters in magnetic-resonance-guided ultrasound focusing

摘要

A magnetic-resonance-guided focused ultrasound system may be calibrated by generating ultrasound foci using ultrasound transducers, establishing coordinates of the foci and of magnetic-resonance trackers associated with the transducers, and determining a geometric relationship between the trackers and the transducers.

主权项

1. A method for calibrating a magnetic-resonance-guided focused-ultrasound system, comprising:
(a) providing a phased array of ultrasound transducers, the array having at least one magnetic resonance (MR) tracker associated therewith at a fixed relative position with respect thereto; (b) establishing MR coordinates of the MR trackers; (c) for each of a plurality of sonication schemes, (i) creating an ultrasound focus, and (ii) establishing parameters indicative of MR coordinates of the ultrasound focus, wherein each sonication scheme is associated with a scheme-specific set of production errors; and, (d) based at least in part on the parameters, determining a geometric relationship between the ultrasound transducers and the MR trackers.