发明名称 |
GENETICALLY ENGINEERED BACTERIUM COMPRISING ENERGY-GENERATING FERMENTATION PATHWAY |
摘要 |
The invention relates to a genetically engineered bacterium comprising an energy-generating fermentation pathway and methods related thereto. In particular, the invention provides a bacterium comprising a phosphate butyryltransferase (Ptb) and a butyrate kinase (Buk) (Ptb-Buk) that act on non-native substrates to produce a wide variety of products and intermediates. In certain embodiments, the invention relates to the introduction of Ptb-Buk into a C1-fixing microoorgansim capable of producing products from a gaseous substrate. |
申请公布号 |
US2017101631(A1) |
申请公布日期 |
2017.04.13 |
申请号 |
US201615293191 |
申请日期 |
2016.10.13 |
申请人 |
LanzaTech New Zealand Limited |
发明人 |
Koepke Michael;Jensen Rasmus Overgaard;Behrendorff James Bruce Yarnton Haycock;Hill Ryan Edward |
分类号 |
C12N9/12;C12N9/02;C12P5/00;C12P7/04;C12P7/42;C12N9/10;C12P7/28 |
主分类号 |
C12N9/12 |
代理机构 |
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代理人 |
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主权项 |
1. A genetically engineered bacterium comprising exogenous phosphate butyryltransferase (Ptb) and exogenous butyrate kinase (Buk) (Ptb-Buk), wherein the Ptb-Buk acts on a non-native substrate to produce a non-native product. |
地址 |
Skokie IL US |