PHARMACEUTICAL COMPOSITION AND DEVICE FOR TREATING PAIN

摘要

The invention relates to a system for the sequential intranasal administration of at least one active ingredient selected from a DR group having at least one side effect of respiratory depression and at least one active ingredient selected from an ADR group that counteracts the respiratory depression that may be induced by the active ingredients of the DR group. The invention also relates to a portable sequential intranasal administration device comprising an intranasal administration system according to the principles of the invention.

主权项

1. A method for sequential intranasal administration of at least one active ingredient selected from a DR group having at least one side effect of respiratory depression and at least one active ingredient selected from an ADR group that counteracts respiratory depression that may be induced by the active ingredients of the DR group, the method comprising:
administering an initial dose of a first active formulation comprising at least one active ingredient from the DR group, in response to an initial actuation of a portable sequential intranasal administration medical device by a patient wishing to receive pharmaceutical administration; and administering at least one subsequent dose of a second active formulation comprising at least one active ingredient from the ADR group or of the first active formulation, in response to at least one subsequent actuation of the portable sequential intranasal administration medical device by the patient wishing to receive the subsequent pharmaceutical administration.