PATTERNED SURFACE

摘要

The present disclosure provides patterned materials that may be useful in reducing certain negative effects associated with damaged tissue in vivo. The patterned materials can modify the healing process, and may minimize the formation of scar tissue. Such effects can provide inhibition of adhesion between tissues and/or reduction of fibrotic encapsulation around implanted medical devices.

主权项

1. A patterned adhesion barrier comprising a base surface, wherein at least a portion of the base surface comprises a plurality of projections attached to the base surface and extending outward therefrom, wherein the projections are irregularly spaced with respect to each other and have an average length to diameter aspect ratio of at least about 5.