Motility-Contrast Imaging for Oocyte and Embryo Viability Assessment

摘要

A method and system is provided for evaluating viability of oocytes and embryos comprising imaging an oocyte or embryo using motility contrast imaging; generating temporal contrast and spatial contrast data for the cells; generating a cell viability value as a function of the temporal and spatial contrast data; and comparing the cell viability value to a predetermined value indicative of a cell suitable for use in an in vitro fertilization program.

主权项

1. A method for evaluating viability of oocytes and embryos comprising:
reversibly immobilizing reproductive cells; detecting intracellular motion within the immobilized cells; generating a measure of dynamic activity of the cells; and comparing the measure of dynamic activity to a threshold indicative of cell viability.