| 发明名称 |
METHODS AND COMPOSITIONS FOR IMMUNOMODULATION |
| 摘要 |
The methods and uses described herein relate to the modulation of the immune system by modulation of Sema3F levels and/or activity, e.g. suppressing allograft rejection or inflammation by administering a Sema3F agonist or increasing an immune response by administering a Sema3F inhibitor. |
| 申请公布号 |
US2017100456(A1) |
申请公布日期 |
2017.04.13 |
| 申请号 |
US201515314970 |
申请日期 |
2015.06.01 |
| 申请人 |
CHILDREN'S MEDICAL CENTER CORPORATION |
发明人 |
BRISCOE David M.;KLAGSBRUN Michael;BRUNEAU Sarah;KOCHUPURAKKAL Nora;NAKAYAMA Hironao |
| 分类号 |
A61K38/17;A61K38/48;C07K16/28;A61K45/06;C07K16/18 |
主分类号 |
A61K38/17 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of suppressing allograft rejection, the method comprising administering a Sema3F agonist to an allograft recipient, whereby immune rejection of the allograft is suppressed. |
| 地址 |
Boston MA US |
