| 发明名称 |
EXTENDED RELEASE COMPOSITIONS OF AN AMINOALKYL NITRATE |
| 摘要 |
The present invention relates to extended release compositions of an amino-C2-C6-alkyl nitrate and of pharmaceutically acceptable salt thereof, in particular 2-aminoethyl nitrate, and to fixed dose combinations with further pharmaceutically active drug substances. 2-Aminoethyl nitrate does not provoke nitrate tolerance, but has a very short half life in physiological systems. |
| 申请公布号 |
US2017100350(A1) |
申请公布日期 |
2017.04.13 |
| 申请号 |
US201615389646 |
申请日期 |
2016.12.23 |
| 申请人 |
CARDIOLYNX AG |
发明人 |
SARTOR Dirk;VANKAN Pierre;STUCKLER Hubert;SCHERHAG Armin |
| 分类号 |
A61K31/131;A61K9/70;A61K9/48;A61K9/20;A61K45/06;A61K9/00 |
主分类号 |
A61K31/131 |
| 代理机构 |
|
代理人 |
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| 主权项 |
1. An extended release composition of an amino-C2-C6-alkyl nitrate and of pharmaceutically acceptable salts thereof, wherein release is over 4-24 hours. |
| 地址 |
Basel CH |
