发明名称 |
6-CHLORINE-SUBSTITUTED IMIDAZO[1,2-A]PYRIDINE CARBOXAMIDES AND THE USE THEREOF AS SOLUBLE GUANYLATE CYCLASE STIMULATORS |
摘要 |
The present application relates to novel 6-chloro-substituted imidazo[1,2-a]pyridine-3-carboxamides, to processes for preparation thereof, to the use thereof, alone or in combinations, for treatment and/or prophylaxis of diseases, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially for treatment and/or prophylaxis of cardiovascular disorders. |
申请公布号 |
US2017101407(A1) |
申请公布日期 |
2017.04.13 |
申请号 |
US201515308200 |
申请日期 |
2015.04.29 |
申请人 |
Bayer Pharma Aktiengesellschaft |
发明人 |
VAKALOPOULOS Alexandros;FOLLMANN Markus;STASCH Johannes-Peter;WUNDER Frank;MARQUARDT Tobias;DIETZ Lisa;LANG Dieter;LI Volkhart Min-Jian |
分类号 |
C07D471/04;A61K31/437;A61K45/06 |
主分类号 |
C07D471/04 |
代理机构 |
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代理人 |
|
主权项 |
1. Compound having the systematic name ent-N-(2-amino-3-fluoro-2-methylpropyl)-6-chloro-8-[(2,6-difluorobenzyl)oxy]-2-methylimidazo[1,2-a]pyridine-3-carboxamide (enantiomer B) and the structural formula and the N-oxides, salts, solvates, salts of the N-oxides and solvates of the N-oxides and salts thereof. |
地址 |
Berlin DE |