发明名称 6-CHLORINE-SUBSTITUTED IMIDAZO[1,2-A]PYRIDINE CARBOXAMIDES AND THE USE THEREOF AS SOLUBLE GUANYLATE CYCLASE STIMULATORS
摘要 The present application relates to novel 6-chloro-substituted imidazo[1,2-a]pyridine-3-carboxamides, to processes for preparation thereof, to the use thereof, alone or in combinations, for treatment and/or prophylaxis of diseases, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially for treatment and/or prophylaxis of cardiovascular disorders.
申请公布号 US2017101407(A1) 申请公布日期 2017.04.13
申请号 US201515308200 申请日期 2015.04.29
申请人 Bayer Pharma Aktiengesellschaft 发明人 VAKALOPOULOS Alexandros;FOLLMANN Markus;STASCH Johannes-Peter;WUNDER Frank;MARQUARDT Tobias;DIETZ Lisa;LANG Dieter;LI Volkhart Min-Jian
分类号 C07D471/04;A61K31/437;A61K45/06 主分类号 C07D471/04
代理机构 代理人
主权项 1. Compound having the systematic name ent-N-(2-amino-3-fluoro-2-methylpropyl)-6-chloro-8-[(2,6-difluorobenzyl)oxy]-2-methylimidazo[1,2-a]pyridine-3-carboxamide (enantiomer B) and the structural formula and the N-oxides, salts, solvates, salts of the N-oxides and solvates of the N-oxides and salts thereof.
地址 Berlin DE