发明名称 |
(S)-3-Amino-4-(difluoromethylenyl)cyclopent-1-ene-1-carboxylic acid, and Related Compounds as GABA Aminotransferase Inactivators for the Treatment of Epilepsy, Addiction and Hepatocellular Carcinoma |
摘要 |
Cyclopentene carboxylic acid-related compounds as GABA-AT inhibitors for treatment of various addictions, disorders and disease states. |
申请公布号 |
US2017101364(A1) |
申请公布日期 |
2017.04.13 |
申请号 |
US201615289480 |
申请日期 |
2016.10.10 |
申请人 |
Silverman Richard B.;Takaya Kenji;Le Hoang V.;Juncosa Jose I. |
发明人 |
Silverman Richard B.;Takaya Kenji;Le Hoang V.;Juncosa Jose I. |
分类号 |
C07C229/48 |
主分类号 |
C07C229/48 |
代理机构 |
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代理人 |
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主权项 |
1. A compound of a formulawherein each of R1 and R2 is independently selected from H, F, Cl, Br and I, providing at least one of R1 and R2 is not H, or a salt thereof. |
地址 |
Winnetka IL US |