| 发明名称 |
BISPECIFIC ANTIBODY FRAGMENTS FOR NEUROLOGICAL DISEASE PROTEINS AND METHODS OF USE |
| 摘要 |
The present invention relates to therapeutic agents comprising bispecific recombinant antibody fragments to selectively clear a protein associated with a neurological disease and methods of use of these therapeutic agents to treat neurological diseases. |
| 申请公布号 |
US2017101463(A1) |
申请公布日期 |
2017.04.13 |
| 申请号 |
US201615332954 |
申请日期 |
2016.10.24 |
| 申请人 |
ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA, ACTING FOR AND ON BEHALF OF |
发明人 |
Sierks Michael;Shen Yong |
| 分类号 |
C07K16/18 |
主分类号 |
C07K16/18 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A bispecific antibody fragment comprising
(a) a first ligand that specifically recognizes a protein associated with a neurological disease, and (b) a second ligand that specifically activates a classical complement pathway component or directly activates microglial cells. |
| 地址 |
Scottsdale AZ US |
