Pharmaceutical for oral delivery comprising MGBG and methods of treating disease

摘要

Disclosed herein are new oral pharmaceutical compositions of MGBG and related polyamine analogs, polyamine biosynthesis inhibitors, polyamine inhibitors of AMD-I and regulators of osteopontin, and their application for the treatment of disease.

主权项

1. A method of treating, or delaying the onset or development of, multiple sclerosis, comprising administering to a subject in need thereof about 25 mg/day to about 350 mg/day of an oral pharmaceutical composition comprising MGBG and at least one pharmaceutically acceptable excipient.