发明名称 Collagen powder and/or collagen-derived powder, and production method for the same
摘要 Disclosed is a collagen powder and/or a collagen derivative powder, which are obtained by dispersing in a hydrophilic organic solvent a crude collagen precipitate which comprises 12 to 50% by mass of a collagen precipitate and/or a collagen derivative precipitate having an average particle size of 1 to 1,000 μm, recovering solids and then drying the solids. By dispersing the crude collagen precipitate in the hydrophilic organic solvent, the resulting precipitates can be dehydrated, so that drying of the thus obtained solids can be done by air-drying. In addition, the resulting collagen powder and/or collagen derivative powder exhibit excellent solubility due to an increased specific surface area and also have excellent ease of handling with the average particle size being 8 to 1,000 μm.
申请公布号 US9617298(B2) 申请公布日期 2017.04.11
申请号 US201113813126 申请日期 2011.07.29
申请人 NIPPI, INCORPORATED 发明人 Tanaka Keisuke;Ogura Takayuki;Hattori Shunji;Matsuda Koichi;Kobayashi Yoshikatsu;Oi Shoji
分类号 C07K1/30;A61K9/14;A61K8/02;A61K8/65;C08J3/14;C08L89/06;A61Q19/00;C08H1/06 主分类号 C07K1/30
代理机构 Birch, Stewart, Kolasch & Birch, LLP 代理人 Birch, Stewart, Kolasch & Birch, LLP
主权项 1. A collagen powder and/or a collagen derivative powder, which are obtained by dispersing in a hydrophilic organic solvent a crude collagen precipitate which comprises 12 to 50% by mass of a collagen precipitate and/or a collagen derivative precipitate having an average particle size of 1 to 1,000 μm, prepared by salt precipitation or isoelectric precipitation of solubilized collagen and/or solubilized collagen derivative, recovering solids and then drying the solids to obtain the collagen powder and/or the collagen derivative powder, wherein the collagen powder and/or collagen derivative powder have an initial dissolution rate of not less than 0.2 mg/min. in a pH 6.5 solution comprising 5 mg of the collagen powder and/or the collagen derivative powder.
地址 Tokyo JP