发明名称 HPLC-system with variable flow rate
摘要 In a high performance liquid chromatography system, wherein a mobile phase is driven through a stationary phase for separating compounds of a sample fluid comprised in the mobile phase, a flow rate of the mobile phase is controlled in dependence on a variation in a control value in the system.
申请公布号 US9618485(B2) 申请公布日期 2017.04.11
申请号 US200712742098 申请日期 2007.11.12
申请人 Agilent Technology, Inc. 发明人 Witt Klaus
分类号 B01D15/08;G01N30/32;F04B11/00;G01N30/22;G01N30/24;G01N30/86 主分类号 B01D15/08
代理机构 代理人
主权项 1. A high performance liquid chromatography (HPLC) system, comprising: a separating device comprising a separating device inlet, a separating device outlet, and a stationary phase for separating compounds of a sample fluid carried in a mobile phase; a mobile phase drive comprising a mobile phase drive outlet in fluid communication with the separating device inlet, the mobile phase drive configured for driving the mobile phase through the separating device at a fluid pressure and a fluid flow rate; and a control unit in signal communication with the mobile phase drive, the control unit configured for: receiving a control value indicative of the fluid pressure in the mobile phase; and based on the control value, maintaining the fluid pressure at the separating device inlet substantially at a set value or within a range including the set value, by controlling the mobile phase drive to vary the fluid flow rate, wherein the control value is selected from the group consisting of: a pressure measured in the mobile phase; a pressure difference between the separating device inlet and the separating device outlet; a control parameter of the mobile phase drive; a temperature measured in the mobile phase; and a combination of two or more of the foregoing.
地址 Santa Clara CA US